Journal article
Development of a porous 3D graphene-PDMS scaffold for improved osseointegration
J Li, X Liu, JM Crook, GG Wallace
Colloids and Surfaces B Biointerfaces | ELSEVIER | Published : 2017
Abstract
Osseointegration in orthopedic surgery plays an important role for bone implantation success. Traditional treatment of implant surface aimed at improved osseointegration has limited capability for its poor performance in supporting cell growth and proliferation. Polydimethylsiloxane (PDMS) is a widely used silicon-based organic polymer material with properties that are useful in cosmetics, domestic applications and mechanical engineering. In addition, the biocompatibility of PDMS, in part due to the high solubility of oxygen, makes it an ideal material for cell-based implants. Notwithstanding its potential, a property that can inhibit PDMS bioactivity is the high hydrophobicity, limiting its..
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Awarded by Australian National Fabrication Facility
Funding Acknowledgements
The authors wish to acknowledge funding from the Australian Research Council (ARC) Centre of Excellence Scheme (CE140100012), the use of facilities at the University of Wollongong Electron Microscopy Centre, support of the Australian National Fabrication Facility (ANFF)-Materials Node for provision of equipment. Prof. Gordon G. Wallace acknowledges the support of the ARC through an ARC Laureate Fellowship (FL110100196). The authors would also like to thank Assoc. Prof. Chee o. Too and Dr. Kerry Gilmore for their valuable comments on the manuscript.